Peptides are short chains of amino acids that can help with anti-aging when applied topically in skincare products. The benefits of peptides vary depending on the type of peptide used. Signal peptides, for example, enhance the production of collagen and elastin, while carrier peptides help deliver vital ingredients to target sites to increase collagen production. Enzyme-inhibitor peptides can block the enzymes that break down collagen, leading to firmer skin. Another type of peptide, neuropeptides, can block the release of neurotransmitters that relay muscle signals, similar to neuromodulators, helping relax facial muscles and minimize expression lines.

When looking for a peptide serum, it is recommended to choose a formula that combines peptides with other beneficial ingredients like hyaluronic acid, ceramides, and glycerin to protect the skin barrier and leave skin feeling plump and smooth. Signal peptides and carrier peptides have the most evidence to support their anti-aging benefits, with copper peptides being among the most common and well-studied signal peptides. Consider your specific skin concerns when choosing a peptide serum, such as opting for a signaling peptide in a hydrating formulation if you are looking for plumper, smoother skin.

Peptide serums are recommended for individuals who already use an antioxidant serum, a retinoid, and sunscreen, as peptides can enhance an anti-aging skincare routine. Peptides play more of an additive role and can offer a preventative effect by stimulating important proteins like collagen. The longer peptides are used, the more benefits can be seen, such as firmer and brighter skin with slowed signs of aging like fine lines and wrinkles. Peptide serums are also a good option for those who cannot tolerate irritating ingredients like retinoids, as they offer a similar ability to stimulate collagen production without the risk of irritation.

Experts in the field of dermatology, such as Carmen Castilla, MD, Melanie Palm, MD, and Jeanette Graf, MD, recommend peptide serums as a beneficial addition to an anti-aging skincare routine. Peptides can have various effects on the skin, depending on the type used, and can help address specific skin concerns like fine lines, wrinkles, and lax skin. By choosing a peptide serum that combines peptides with other beneficial ingredients and considering individual skin concerns, individuals can experience the anti-aging benefits of peptides while maintaining a healthy and radiant complexion.

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