Scientists at the University of Southern California’s Keck School of Medicine in Los Angeles have for the first time identified changes in the brain in migraine using an MRI machine. The results of the work will be presented at the annual meeting of the Radiological Society of North America (RSNA), a brief review leads Medical Xpress.
The team used 7T ultra-high-field MRI to study structural changes in tiny blood vessels in various types of migraine. The authors note that this is the first study of its kind using such a precise technique. A total of ten people with chronic migraine, ten people with episodic migraine, and five healthy controls were examined. All participants were between 25 and 60 years old.
The scientists then looked at the magnified perivascular spaces in the semi-oval center (centrum semiovale, the central region of the white matter) and the basal nuclei of the brain. In addition, subjects were asked about the duration and severity of the disease, symptoms, the presence of aura and the area of headache.
It turned out that the number of enlarged perivascular spaces in the semioval center was significantly higher in patients with migraine compared with healthy volunteers. At the same time, an association of increased indicators of the perivascular space with hyperintense lesions of the white matter in patients with migraine was noted. Such pronounced changes in the brain of patients with migraine may indicate a violation of the lymphatic system in this organ.
However, it was not possible to find out whether such changes affect the development of migraine or are its result. In the future, experts want to continue observations with more people and longer time frames to study the correlation between structural changes in the brain and the development and type of migraine.